Milk Thistle Benefits: 15 Ways This Super Herb Can Improve Your Health

By Nikki Lyn Pugh

Reading Time: 8 minutes

This article discusses emerging/ongoing science and research. It is intended for general informational purposes only. This content is unrelated to products offered by Organixx and does not contain any representations about the performance of such products.

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Do you want to help your body’s built-in detoxification system? Then, simply put, supporting your liver is a must-do. One well-known natural herb for helping to detoxify the liver is milk thistle (Silybum marianum). Milk thistle is often referred to as the “liver herb” and taking it is a fantastic way to give this vital detoxifying organ (and your whole body) that extra boost. Read on to discover more about how milk thistle benefits your health.

What Is Milk Thistle?

Truth be told, milk thistle isn’t much to look at. You might even mistake it for a weed if you saw it in your backyard, with its thorny leaves and bulbous, purple flowers.
Seeds of a milk thistle with flowers on wooden tableIn fact, in many areas outside of its native land (Southern Europe through Asia), it’s considered an invasive weed.

For thousands of years, however, people have used the leaves, seeds, and flowers of Silybum marianum as a liver detoxifier and overall health tonic.

Other names for milk thistle include Mary thistle, blessed thistle, Marian thistle, Mediterranean milk thistle, variegated thistle, Saint Mary’s thistle, and Scotch thistle. (It should not be confused with holy thistleCnicus benedictus – which is a different thistle that also boasts many health benefits.)

Whatever it goes by, what makes milk thistle such an amazingly healthy herb are phytonutrients called flavonolignans. In particular, a combination of three flavonolignans which are collectively known as silymarin. They are:

  • silybin
  • silydianin
  • silychristin

Silymarin consists of about 50% silybin, with silydianin and silychristin making up the rest.

The Best Sources of Silymarin

The seeds and flowers of the milk thistle plant are an especially potent source of silymarin, but the leaves can contain it as well. Milk thistle can be found in the whole dried form in herb shops and used as a tea. Increasingly, however, it is powdered and used alone or in conjunction with other liver-supporting herbs in specific formulas.

Supplementing with milk thistle can be a great addition to your everyday routine, especially during times when your liver needs a little more support (like just after the holidays or a vacation where you over-indulged).

Also, as we shall see below, studies have found that those with specific liver problems and conditions such as autoimmune diseases, fatty liver disease, heavy metal toxicities, and even cancer (e.g., breast cancer) can benefit tremendously from adding milk thistle to their existing healing protocol.

Milk Thistle Benefits: 15 Reasons Why Milk Thistle Is So Good for You

Milk thistle can be a great overall tonic for health every day. Apart from a little upset stomach if you take too much, there are no known side effects. Of course, if you have a known allergy to milk thistle, you’ll need to avoid it.

Always remember that plants can be potent, so be sure to seek medical advice from your healthcare provider before taking – especially if you have special health concerns or are on any medication. For example, milk thistle has been reported to counteract some chemotherapy drugs.

#1: Milk thistle detoxifies the liver.

There is a reason why milk thistle is called the “liver herb.” The flavonoid combo of silymarin (and especially the phytonutrient silybin) can help rebuild liver cells while it removes toxins from that organ at the same time.

The liver is central to detoxification in the body, such as storing key hormonal substances, metabolic processes, and cleaning out the blood.

A systematic review of clinical studies of milk thistle requested by the National Center for Complementary Medicine (part of the National Institutes of Health) back in 2000 reported that:

“Evidence exists that milk thistle may be hepatoprotective through a number of mechanisms: antioxidant activity, toxin blockade at the membrane level, enhanced protein synthesis, antifibriotic activity, and possible anti-inflammatory or immunomodulating effects.”

A 2005 report published in Alternative Medicine Review found that the flavonoids in milk thistle act to protect the liver by significantly boosting its resistance to “toxic insult.”

#2: Milk thistle is GREAT for the immune system.

Because it provides such support for the liver, milk thistle also fortifies the immune system and can even help reduce the effects of aging.

This is because milk thistle is also a super antioxidant, removing pollutants, going after pathogens, and preventing free radical damage in the body. The research suggests that milk thistle supplementation can help support the body against some of the most common disease conditions.

#3: Milk thistle can help detoxify heavy metals.

Milk thistle has been shown to help reverse damage to the liver caused by heavy metals such as mercury, arsenic, cadmium, and lead. It can protect against these metals because of the boost it gives to the liver.

Heavy metal toxicity is a serious issue that most people face at some point during their lives, because of pollutants in the air and water, as well as amalgam dental fillings, which can contain up to 50% mercury.

Heavy metal toxicity is a serious issue as it can lead to:

memory loss

mood changes

cognitive decline



Milk thistle supplementation, as well as healing the gut through probiotics, can aid the body in eliminating these toxins and restoring balance.Capsules of milk thistle

#4: Milk thistle helps prevent abnormal cell growth.

The antioxidant power of silymarin also helps to protect your body from free radical DNA damage that can lead to abnormal cell growth.

#5: Milk thistle boosts glutathione production.

Silymarin can boost the production of the super-antioxidant glutathione, which is found in its most potent form when it is produced inside the body. Glutathione is produced in part within the liver, and milk thistle has been found to strengthen liver cell walls.

#6: Milk thistle can help lower inflammation.

A January 2017 study discovered that milk thistle helped to reduce the “inflammatory cascade” associated with hepatitis C while at the same time modulating the immune system and acting as an anti-viral agent, which can also lead to inflammation reduction system-wide.

#7: Milk thistle can help to lower your risk of obesity.

Obesity is often the result of a vicious cycle of poor lifestyle choices, poor metabolism, poor detoxification, low energy, high toxic load, and inflammation. By supporting detoxification pathways, those who suffer from obesity can receive a helping hand with their weight loss goals.

A 2004 report published in The Journal of Alternative and Complementary Medicine hypothesized that human exposure to chemical toxins can have damaging effects on weight control mechanisms within the body and may even be a major factor in the global obesity epidemic.

Protecting the body from these toxins, which milk thistle does, may result in a normalization of weight regulation functions.

#8: Milk thistle may be beneficial for people with diabetes.

While milk thistle’s benefits to the liver have been known for quite some time, researchers are just beginning to discover its effects for helping to regulate blood sugar levels and insulin resistance, which may benefit those with type 2 diabetes.

A 2007 study conducted by the Universidad de Salamanca in Spain found that milk thistle has “anti-hyperglycemic properties” and may help regulate “liver gluconeogenesis.”

#9: Milk thistle can help with depression.

Liver overload can lead to a neurotoxic buildup in the brain, which can exacerbate and even cause mental imbalances such as depression, anxiety, bipolar disorder, and schizophrenia.

By supporting detoxification in such a major way, milk thistle supplementation can help to turn depressive conditions and other neurological imbalances around.

Sixteenth-century botanist John Gerard declared St. Mary’s thistle (i.e., milk thistle) “the best remedy that grows for all melancholy diseases.”

#10: Milk thistle can make your skin glow.

Studies have shown that milk thistle can help prevent skin damage such as dark spots as well as lines and even wrinkles by protecting from UV light. Again, this is because of its antioxidant properties, which also help protect joint tissue health.

#11: Milk thistle can help you detoxify from too many pharmaceutical pain relievers.

Because of all the support it provides for the liver, milk thistle can assist with detoxing from heavy pharmaceutical use, helping you to avoid the dangerous side effects of long-term use.

A 2010 study conducted by the University Magna Graecia in Spain found that silymarin from milk thistle helps to counter the negative side effects of heavy acetaminophen use.

#12: Milk thistle can help you after too much alcohol consumption.

Several studies have zeroed in on milk thistle’s protective effects against liver disease, especially cirrhosis caused by excessive alcohol consumption.

Many studies suggest that it can even help to reverse the damage caused by alcohol consumption. Just to be clear, however, taking milk thistle is not a replacement for cutting back if you drink in excess on a regular basis.

#13: Milk thistle can help clear out gallstones.

Milk thistle can be a great boost for your gallbladder. The gallbladder is a small, oblong-shaped organ that sits just below the liver and is responsible for the production of bile – a high-alkaline fluid essential for digestion.

Many studies, including a 2011 meta-analysis published in the Journal of Advanced Pharmacy Education & Research, have linked it to a reduction in gallstones.

Studies also suggest that milk thistle can be beneficial for those with cholestasis, a common condition where the gallbladder stops making bile, or bile production is severely limited.

#14: Milk thistle can help turn around fatty liver disease.

It’s good news that the conventional medical community has acknowledged the healing power of milk thistle enough that it has been approved as a “therapeutic treatment” for many kinds of liver disease, including fatty liver.

Fatty liver is caused by a build-up of fat in the liver which causes the liver’s function to wane and can lead to diabetes, cirrhosis, and liver cancer.

While fatty liver disease was once associated only with alcoholics, it’s now of major concern to an increasing number of individuals in industrialized countries. Fatty liver is associated with eating the standard American diet (SAD) and possibly with GMOs as well.

#15: Milk thistle is great for individuals with autoimmune disease.

Many conventional treatments for the dozens of autoimmune conditions that exist today, such as lupus, rheumatoid arthritis, and MS rely on harsh drugs that act to suppress certain mechanisms of the immune system.

Natural substances such as milk thistle help to balance the immune system so that proper communication and function can gently and gradually be restored.

Milk thistle’s liver-boosting properties can also be of great benefit to autoimmune disease sufferers, who often have problems with sluggish detoxification pathways.

Many expert protocols for common autoimmune conditions such as Hashimoto’s thyroiditis and diabetes incorporate milk thistle in some way. If you have an autoimmune condition, be sure to ask your naturopathic physician about how milk thistle can help you.

By now, you should be convinced of not only the amazing milk thistle benefits but also how supporting your liver can help your entire body stay healthy and disease-free. There’s no doubt about what generations of Europeans and others have known for so long: the humble plant known as milk thistle is a true gift from nature!

Milk Thistle is an Ingredient in Organixx Liver & Kidney Detoxx

Milk thistle is the first ingredient in Organixx Liver & Kidney Detoxx, part of the 2-step system in the Organixx Cleanse & Detoxx Kit. It’s one of six powerful botanicals selected for their ability to gently detox your system for robust immune protection all year round.

Organixx Cleanse & Detoxx is a two-step formula that provides a gentle yet powerful full-body detox using organic botanical ingredients. Naturally purge your body of toxins, chemicals, free radicals, heavy metals, waste, as well as bacteria, and pesticides. Easily cleanse your colon, liver, kidneys, lungs, and lymphatic system resulting in increased energy, and better digestion with more nutrient absorption, in addition to improved immunity, mental clarity, and overall health and wellbeing.

Organixx Cleanse & Detoxx
Nikki Lyn Pugh
Nikki Lyn Pugh, MFA, INHC is a natural health researcher and writer. She is also an integrative nutritional health coach specializing in autoimmune conditions, chronic stress, and energy medicine. She loves to inspire people to become empowered with their health through education and gentle guidance. Nikki lives and works in Cottonwood, AZ, with her bunny "Mr. Dot."

Article Summary

  • For thousands of years, people have used milk thistle as a liver detoxifier and overall health tonic.

  • Supplementing with milk thistle can be a great addition to your everyday routine.

  • Studies have found that people with a number of specific health conditions can benefit tremendously from adding milk thistle to their existing healing protocol.

  • 15 reasons why milk thistle is so good for you:

    1. It helps detoxify the liver
    2. It’s great for the immune system
    3. It can help detoxify heavy metals
    4. It helps prevent abnormal cell growth
    5. It boosts glutathione production
    6. It can help lower inflammation
    7. It can lower your risk of obesity
    8. It may be beneficial for those with type 2 diabetes
    9. It can help with depression
    10. It can make your skin glow
    11. It can help you detoxify from too many pharmaceutical pain relievers
    12. It can help you after too much alcohol consumption
    13. It can help clear out gallstones
    14. It can help turn around fatty liver disease
    15. It’s great for individuals with autoimmune disease
  • Milk thistle is a key ingredient in our Organixx Liver & Kidney Detoxx formula.


  1. I've always heard that if someone is allergic to ragweed as I am, they should avoid milk thistle because it's in the same family as ragweed. Do you have any recommendations for a substitute for milk thistle that would still do the whole detox job?

  2. Milk thistle should not be used by pregnant or breastfeeding women. People with a history of hormone-related cancers, including breast, uterine, and prostate cancer, should not take milk thistle. DO NOT take milk thistle if you are allergic to ragweed, chrysanthemums, marigolds, chamomile, yarrow, or daisies.

  3. I heard Tauroursodeoxycholic Acid works as well. I have a bottle of milk thistle but haven't really taken it very much. Do you think I should just stick with that or buy this other thing as well? I'm using it for liver detox and to lose weight. I'm in my 50's.

    • Hello Mary,

      Regarding your question, unfortunately Organixx cannot diagnose, treat, or give you advice regarding your health and individual use of our products.

      If you have questions regarding individual use of our product, please consult with your trusted health professional or practitioner.

      If you do not have a doctor, we invite to you to check out our own Dr. Melissa Gallagher:

      Have an awesome day!

  4. The links you have provided do not take us to the page to actually purchase your "Daily Detox" product and I cannot find it by searching on your website. It says, "Page Not Found

    The page you requested does not exist."

    • Hi Misha,

      We're very sorry about that. Thank you for pointing this out. Please know, that it has been reported to our Marketing Team.

      Also, be on the lookout for a new Organixx Detox product to be announced in the coming weeks.

      Thanks so much for being here with us. Wishing you a happy & healthy day!!

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