Can I Take Collagen And Multivitamins Together? A Quick Guide

Medically Reviewed by Shane Mouser, RPh, Pharm.D. Shane Mouser, RPh, Pharm.D.

Shane Mouser is a Nashville-based registered pharmacist specializing in wellness and chronic disease management through medication therapy management

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By Jonathan Hunsaker

Reading Time: 12 minutes

This article discusses emerging/ongoing science and research. It is intended for general informational purposes only. This content is unrelated to products offered by Organixx and does not contain any representations about the performance of such products.

Can I Take Collagen And Multivitamins Together?

Well, many people are looking for ways to improve their overall health, and one way to do this is by taking collagen supplements. Collagen is a protein that is found in the skin, bones, and connective tissues, and it plays a vital role in maintaining the structure of the body.

Some people may wonder if they can take collagen and multivitamins together. In this guide, we’ll explore the potential benefits and risks of taking collagen supplements in combination with multivitamins.

What exactly is collagen? 

Before we take a look at combining the benefits or risks of combining collagen and multivitamins, it’s important to first understand what collagen actually is. Collagen is a protein that can be found in various parts of the body. It plays an important role in maintaining the structure and integrity of these areas, as well as keeping them functioning properly.

Can I take collagen and multivitamins together? 

Now that we have a better understanding of what collagen is, let’s take a look at whether or not it’s safe to take collagen and multivitamins together. There’s no definitive answer to this question, as there are certain vitamins which can pair with collagen and others that should be avoided.

What vitamins and minerals are great with collagen? 

There are a handful of vitamins and minerals that can complement collagen supplements and can help to promote overall health. Some of these include:

Vitamin A

One of the key vitamins when it comes to collagen is vitamin A. Not only does it aid in collagen production, it can also help to improve the appearance of wrinkles and other signs of aging. Adding Vitamin A-rich foods like leafy greens, carrots, and sweet potatoes or a Vitamin A supplement can help to improve collagen production.

Vitamin C

Vitamin C is another important vitamin for collagen production and can be easily incorporated into your diet by way of foods or supplements. Vitamin C has been shown to stabilize collagen mRNA, which is necessary in order for collagen to properly synthesize for the repair of damaged skin.

Zinc 

Another way to increase the benefits of collagen supplements is by increasing the amount of zinc in your diet. Zinc is a nutrient which is found in our bodies and aids the immune system as well as metabolism functions. From healing wounds to being a factor in our sense of taste and smell, Zinc also is a cofactor in the production of collagen. Playing a vital role in collagen synthesis, Zinc is known to activate a protein called collagenase which allows cells in your body to remodel collagen when attempting to heal lacerations. 

L-Arginine 

One other vitamin or supplement that can be taken along with collagen supplements is L-Arginine, which can help to increase blood flow and can aid in collagen production. Many foods such as red meat, poultry, nuts, and seeds contain L-Arginine, making it easy to incorporate into your diet.

Whey Protein Powder 

Adding a whey protein powder can also help to increase collagen production in the body. Whey protein is a highly bioavailable source of protein, which can be easily digested and absorbed into the body.

Hyaluronic Acid 

Finally, Hyaluronic acid can be used in conjunction with collagen which can improve hydration and can help to reduce the appearance of wrinkles. A naturally occuring substance, the amount of Hyaluronic acid begins to decrease as we age. Hyaluronic acid provides a moisture-rich setting in which collagen is able to stretch without breaking–or in other words, provides your skin with elasticity. 

What vitamins and supplement combos should I avoid? 

While there are numerous vitamins and minerals that can complement collagen supplements, there are also some that can counteract their effects. Some examples of vitamins or supplements to avoid when taking collagen include:

Calcium and Magnesium 

While both calcium and magnesium are essential for bone health, they can actually have a negative effect on collagen production. This is because they can compete with each other for absorption in the gut, which can lead to deficiencies in either or both of these minerals. Additionally, collagen can raise levels of calcium and lead to something that is known as hypercalcemia which symptoms include nausea, constipation, fatigue and vomiting. 

Copper and Zinc 

Copper and zinc are two important minerals that are required for the production of collagen. However, taking supplements that contain high levels of these minerals can actually have a negative impact on collagen production. When taken in large amounts, copper and zinc can interfere with the body’s ability to process vitamin C, which is essential for collagen synthesis. In addition, high levels of copper and zinc can promote the formation of harmful free radicals, which can damage skin cells and lead to premature aging.

Fish oil and Ginkgo Biloba

Fish oil supplements are a great source of omega-3 fatty acids, which have numerous benefits for the skin. However, taking fish oil supplements can actually decrease the amount of collagen in the skin. This is because omega-3 fatty acids can interfere with the body’s ability to produce collagen. In addition, ginkgo biloba supplements can also have a negative impact on collagen production. This is because ginkgo biloba can inhibit the activity of an enzyme called collagenase, which is responsible for breaking down collagen.

Iron and Green Tea 

Iron can also have a detrimental effect on collagen production. This is because high levels of iron can actually lead to the formation of free radicals, which can cause damage to skin cells and contribute to premature aging. Similarly, green tea can decrease collagen levels in the body due to its antioxidant properties. 

Melatonin and St. John’s Wort 

Melatonin can negatively impact collagen production as it can interfere with collagen synthesis and can actually cause the breakdown of certain components of your skin tissues. In addition, St. John’s Wort can decrease the amount of vitamin C in the body, which can lead to decreased collagen levels and weakened skin cells.

Red Yeast Rice and Niacinamide

Red yeast rice can have a number of negative effects on collagen production. This is because it can increase the levels of cholesterol in the body and can actually stem cellular repair. Additionally, niacinamide can also decrease collagen levels in the skin and can lead to the breakdown of certain components of your skin tissues.

Vitamins A, D, E vs. Vitamin K 

Vitamin A can have a number of negative effects on collagen production. It can actually increase the levels of free radicals in the body, damaging skin cells and can lead to premature aging. In addition, vitamin D can also decrease the amount of collagen produced by your skin cells, while vitamin E can promote the breakdown of collagen and disrupt the production of new collagen fibers. 

However, vitamin K can actually help to promote collagen synthesis and can protect your skin from the damaging effects of free radicals. As such, it is important to take a variety of different vitamins in order to maintain healthy collagen levels.

Potassium and Calcium 

Potassium and calcium are two minerals that are essential for the production of collagen. However, taking supplements that contain high levels of these minerals can actually have a negative impact on collagen production. Potassium and calcium can compete with each other for absorption in the gut, which can lead to deficiencies in either or both of these minerals. Additionally, high doses can also lead to unwanted side effects, such as nausea, fatigue and digestive issues.

Vitamin C and Vitamin B12 

Vitamin C is a big part of collagen production, but taking large doses of vitamin C can actually have a negative impact on your natural production. This is because vitamin C can interfere with the body’s ability to process copper, which is necessary for collagen synthesis. Additionally, vitamin B12 can also have a negative impact on collagen levels as B12 can actually inhibit the activity of collagen-producing cells and can disrupt collagen synthesis.

What else do I need to know regarding taking collagen supplements? 

It’s important to note that there are a number of different factors that can impact collagen production. Here are a few things you should know before you start taking collagen supplements: 

You can take collagen in different forms

There are a number of different ways to take collagen supplements in order to reap their benefits. You can take collagen in pill form, you can add collagen powder to your food or drinks, or you can use collagen creams and lotions. 

Collagen supplements have different levels of quality

When you’re looking for collagen supplements, it’s important to choose a high-quality product. The quality of the collagen can impact its effectiveness so make sure to look for collagen that is derived from grass-fed, pasture-raised animals and that has been hydrolyzed into smaller peptides for easy absorption.

You can also get collagen from food sources

Diet and nutrition play such an important role in our lives and should come as a top priority, whether you take vitamins and supplements or not. In addition to taking collagen supplements, it’s important to get plenty of collagen-rich foods in your diet. Some good sources of collagen include grass-fed meat and poultry, bone broth, eggs, and fish such as salmon and sardines. 

Timing matters

If you’re looking to get the most out of your collagen supplements, timing can play an important role. For best results, make sure to take your collagen supplement at least 30 minutes before eating or 2 hours after a meal. This can help ensure that the collagen is properly absorbed into your body and can give you the most benefit.

Key Vitamins and Minerals Your Body Needs

There are a number of different vitamins and minerals that can help to promote healthy collagen levels in your body. To reap the most benefits from your collagen supplements, it is important to make sure that you get enough of these key vitamins and minerals in your diet. This can be done easily by following a well-balanced, healthy diet that includes plenty of fruits, vegetables, and whole foods. 

Here are some of the key vitamins and minerals your body needs: 

Vitamin B1 (Thiamine or Thiamin)

Vitamin B1, also known as thiamine or thiamin, is a water-soluble vitamin that is essential for the function of our bodies. It’s involved in a number of different biochemical processes, including the production of energy and the metabolism of proteins, carbohydrates and fats. Additionally, vitamin B1 plays a key role in collagen production, helping to maintain the structure and function of your skin. 

Vitamin B2 (Riboflavin)

Vitamin B2, or riboflavin, is another important water-soluble vitamin that can help to promote healthy collagen levels. Vitamin B2 can help to support the production of collagen and can also protect against oxidative stress and damage from free radicals.

Vitamin B3 (Niacin)

Vitamin B3, also known as niacin, can be found in a variety of food sources. Vitamin B3 is important for the proper function of our bodies, helping to support energy production and overall metabolism. It can also help to maintain healthy collagen levels and can protect against DNA damage.

Vitamin B6

Like the other B vitamins, vitamin B6 is an important nutrient that can help to promote healthy collagen production in your body. Vitamin B6 can help to support protein metabolism and can also protect against oxidative stress. Additionally, it can play a key role in collagen synthesis and can assist with the formation of skin proteins.

Vitamin B12

Vitamin B12 is very similar to vitamin B6 in that it can also play a vital role in collagen production and can help to promote healthy skin function. It can also protect against oxidative stress and can support the synthesis of amino acids, which are important building blocks for collagen.

Vitamin C

Vitamin C is a powerful antioxidant that can help to reduce oxidative stress and can play a role in collagen synthesis. Vitamin C can also help to support healthy connective tissue by increasing collagen levels within your body. This can help keep your skin looking youthful and can help to improve your overall health. 

Calcium

Calcium is a mineral that is essential for the health of our bones and teeth. It’s also important for the function of other tissues and organs in our bodies. In addition to taking collagen supplements, it’s important to make sure you’re getting enough calcium in your diet. Some good sources of calcium include dairy products such as milk, yogurt and cheese, as well as leafy green vegetables, tofu and certain types of fish.

Chromium

Chromium is another important mineral that can help to support healthy collagen production in your body. It can also play a key role in maintaining blood sugar levels and can help to reduce oxidative stress. Some good food sources of chromium include egg yolks, potatoes and oysters. 

Vitamin D

Vitamin D is an important vitamin that can help to promote healthy collagen levels. This essential vitamin can also help to support the absorption of calcium, which is essential for healthy bones and teeth. Additionally, vitamin D can help to reduce inflammation and can protect against oxidative stress. 

Vitamin E

Vitamin E is a powerful antioxidant that can help to reduce inflammation and can support healthy collagen production in your body. Vitamin E can also protect against oxidative stress, helping to maintain the structure and function of your skin. You can find vitamin E in a variety of different food sources including nuts, seeds, eggs and avocados. 

Folic Acid

Folic acid is a water-soluble vitamin that can help to promote healthy collagen production in your body. Folic acid can also play a role in DNA synthesis, helping to maintain the structure and function of your cells. You can find folic acid in a variety of food sources including leafy green vegetables, legumes, nuts and seeds. 

Vitamin K

Vitamin K is an important vitamin that can help to support healthy collagen production in your body. Vitamin K also plays a role in bone health and can help to reduce the risk of osteoporosis. Additionally, vitamin K can help to protect against oxidative stress and can improve the elasticity of your skin. 

Iodine

Iodine is an essential mineral that can help to promote healthy collagen production in your body. Iodine can also play a role in thyroid function and can help to protect against oxidative stress. Some good food sources of iodine include seafood, seaweed, eggs and dairy products. 

Iron

Iron is an important mineral that is essential for the health of our bodies. It can help to support a variety of different functions in our bodies, including collagen production. Iron can also play a role in energy production and can help to reduce inflammation. Some good food sources of iron include meat, poultry, fish, legumes and nuts.

Magnesium

Magnesium is another mineral that can be found in a variety of food sources. It’s involved in over 300 biochemical reactions in our bodies and can help to support a number of different functions. Magnesium can help to promote healthy collagen levels and can also assist with the production of new collagen fibers. Additionally, it can help to protect against oxidative stress and can support healthy skin function.

Potassium

Potassium can also be found in a variety of foods, and it can help to promote collagen production. Potassium can assist with the synthesis of proteins that are important for healthy skin function and can support the health of your connective tissue. Additionally, it can help protect against oxidative stress and can support overall health.

Selenium

Selenium is a trace mineral that can be found in a variety of food sources such as fish, meat, poultry and eggs. It’s an important nutrient that can help to support healthy collagen levels and can also assist with the production of new collagen fibers. Selenium also helps to protect against oxidative stress and can play a role in DNA repair.

Zinc

Zinc is another essential mineral that can promote collagen production by acting as a cofactor for enzymes involved in collagen synthesis. Getting enough zinc in your diet can help support healthy, vibrant skin and can help to preserve the structural integrity of your connective tissues. 

In Conclusion

Collagen is an important protein that can provide a number of benefits for our health. At the same time, multivitamins also offer a range of important nutrients that can help to support collagen production and promote overall health. With the right diet and supplementation, and the correct pairing of minerals and vitamins, you can support optimal collagen production and enjoy youthful, glowing skin!

For more information, check out our other informative posts, podcasts, and browse our selection of premium collagen supplements! 


Organixx Clean Sourced Collagens blend contains five types of collagen from four sources. What’s more, it’s combined with targeted nutrients such as zinc, vitamin C, and vitamin B6 which specifically enhance the bioavailability and potency of collagen. Clean Sourced Collagens is formulated from the ground up to enhance and support your body’s natural ability to heal and rebuild itself from the INSIDE out.

Organixx Clean Sourced Collagens

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