Collagen With Hyaluronic Acid: Should You Take It?

Everyone’s heard about collagen and hyaluronic acid for skincare. But have you ever considered taking collagen with hyaluronic acid as part of your daily routine?

With the number of collagen products on the market today that specifically advertises collagen with added hyaluronic acid, it’s understandable why one might be curious.

In this article, we’ll dive into whether collagen with hyaluronic acid is right for you and what benefits you can get from taking both of these together. 

What is Hyaluronic Acid, Exactly?

Hyaluronic acid is a natural molecule found in your body, primarily in the skin, and it plays an important role in maintaining moisture and elasticity. 

You can think of hyaluronic acid as being like a water magnet. It draws moisture into itself and helps to retain that moisture within the skin cells. This helps keep your skin hydrated, plump, and youthful looking.

Hyaluronic acid is also known to aid in wound healing, tissue repair, and collagen formation which further contributes to the maintenance of a healthy, glowing complexion.

Why You Need Hyaluronic Acid

Hyaluronic acid is naturally produced and found in the fluids that lubricate and cushion our joints. It’s critical for maintaining healthy joints and providing cushioning for our bones.

It’s a key component of skin tissue and one of the main reasons why our skin looks healthy, smooth, and plump.

Hyaluronic acid delivers nutrients to our tissues, helping with wound healing and regeneration. Hyaluronic acid has anti-inflammatory properties to keep our bodies functioning optimally.

Given all of these incredible benefits, you can understand why hyaluronic acid is so necessary for us.

Hyaluronic Acid and Skin Aging

Hyaluronic acid is a popular component in skin care products due to its amazing ability to delay the effects of aging. Hyaluronic acid works by helping skin cells draw and retain moisture.

By locking in water and forming a protective film over the surface of the skin, hyaluronic acid helps keep the skin looking firm and supple for longer. 

It also plays an important role in stimulating the production of collagen, which is necessary for skin health, healthy hair, and well, the mobility and functioning of our body.

As we age, the amount of hyaluronic acid in our skin begins to decrease. By replenishing our hyaluronic acid levels, we are able to slow down the visible signs of aging.

Hyaluronic Acid and Acne

Hyaluronic acid has been gaining lots of attention lately as a treatment for acne. Hyaluronic acid works to reduce the appearance of scars left over from drying out active acne.

What makes it so special is its ability to hold up to 1000 times its weight in water, providing the skin with intense and lasting hydration. This extra moisture helps clear out clogged pores that are susceptible to breakouts!

Regular use of hyaluronic acid has proven to reduce breakouts by providing intense moisture deep into the epidermal layers of the skin.

Hyaluronic acid offers properties that help reduce oil production, making it less likely that acne will become worse over time. 

Hyaluronic acid helps promote collagen production which can help fill in any gaps left behind on the surface of your skin, further improving the look of pockmarks from old acne spots. This anti-aging ingredient is definitely something worth trying out if you’re dealing with persistent breakouts!

Is it Good to Use Hyaluronic Acid?

Hyaluronic acid is a great choice for those interested in maintaining or improving their skin health. It can be used to supplement the body’s own production of hyaluronic acid when it begins to slow down. A natural occurrence in our 40s.

Hyaluronic acid’s unique molecular structure allows it to work as an intensive moisturizer while also soothing inflammation.

The use of hyaluronic acid helps stimulate the production of collagen and elastin, which are important for overall skin health as well as for creating firmness and avoiding wrinkles.

By incorporating this clinically proven safe and effective natural substance into your skincare regimen you can enjoy many benefits!

How Can I Take Hyaluronic Acid?

If you’re looking to try taking hyaluronic acid, either through a supplement or as part of your regular beauty routine, there are a few different forms it can come in.

Most commonly you’ll find it as a pill or serum, which is the easiest and most direct way to incorporate it into your beauty regimen.

However, you can also find a hyaluronic acid powder if that suits you better. These dietary supplements are easy to find and even easier to add to your daily regime.

If using a serum, you can apply it topically once or twice daily as directed by instructions on the product packaging.

No matter which forms of hyaluronic acid you take, its anti-aging properties make it an essential addition to any skincare routine!

Why Should You Take Hyaluronic Acid With Collagen?

Collagen is one of the most important proteins in your body, playing an essential role in the health and maintenance of your skin, bones, joints, and connective tissue.

Taking hyaluronic acid with collagen can help supplement the reduced levels of both substances over time, providing multiple benefits for our bodies.

Hyaluronic acid works to lock in moisture within tissues so that our skin remains hydrated and supple while collagen supports elasticity, creating a more youthful look. Combining the two is like a daily multivitamin for your body. 

Supplementing with collagen hyaluronic acid can help support joint comfort and mobility, reduce wrinkles, encourage radiant-looking skin, promote healthy blood vessels, support strong healthy nails and healthy hair and enhance overall immunity supporting our health for years to come!

How We Select Supplements

It can often be challenging to decide which supplement is the best for you. It’s important to do your due diligence to help you understand what to look for in a quality supplement.

Determine your specific goals and read up on the available products so you can make an educated decision on what best suits your individual needs. You should also decide which type of supplement will best fit your lifestyle.

Taking time to assess what will benefit you most and remembering your goal will ensure you end up with the product that is ideal for you.

Orally Ingested Or Topical?

The benefits of collagen and hyaluronic acid can vary depending on whether they are administered orally or applied topically. When combined you get collagen hyaluronic acid supplements which improve your health on the outside as well as the inside. 

When taking these ingredients orally, the body finds and absorbs them easier because it is broken down into smaller components, providing nourishment to the entire body systems—this often being helpful for joint pain relief, brain function, muscle soreness, and antioxidant protection against oxidative damage while promoting skin health and healthy hair.

Topical applications are better for more localized areas such as facial wrinkles or age spots. For these specific cases, a concentrated formula helps more than ingesting a supplement in order to target these concerns directly. 

What to Look For in a Collagen Supplement

When choosing a collagen supplement, there are a few key criteria to consider. The most important ingredients to look for are vitamin C, collagen peptides, and amino acids—all of which will help replenish your body’s collagen production.

Most collagen supplements are made up of either bovine collagen peptides or marine peptides. These vital proteins, collagen peptides are an essential ingredient in supplements to boost the many benefits within.

The most popular collagen types are Type I, Type II, Type III and Type IV. Make sure to read the labels to understand what collagen type or collagen types make up the supplement to know what exactly the collagen peptides are targeting—skin, bones, joints, digestive, etc. 

More and more people are choosing a combination collagen hyaluronic acid supplement to powerfully enhance the health benefits of these stand-alone supplements.


When it comes to forms of collagen supplements, there are several options available to suit various needs.

Some common supplement forms include:

Depending on your preferences and lifestyle, some might make more sense for you than others. 

Although collagen powder is probably the most popular form, whatever your preference is, you’re sure to experience results.

Ingredients & Potential Interactions

While collagen supplements can be incredibly beneficial to your diet and overall health, it’s important to understand the key ingredients and any potential interactions that could come with them.

Collagen supplements are typically composed of either marine or bovine collagen peptides, amino acids such as glycine, lysine, and proline, other minerals like magnesium and calcium, vitamin C and vitamin E, plus plant extracts like turmeric or green tea.

While these ingredients are all likely safe on their own, there is potential for interactions if you’re taking other medications.

As an example, marine collagen can have adverse reactions when taken alongside anticoagulant drugs like warfarin. It can increase the effects of the drug and therefore lead to unwanted side effects such as excessive bruising and bleeding.

Make sure to always check the label for any potential interactions before committing to taking any supplement!

When Should I Talk to My Healthcare Provider About Hyaluronic Acid?

If you are considering taking a supplement or trying an over-the-counter product that contains hyaluronic acid, it is important to talk with your healthcare provider.

Although hyaluronic acid is generally safe, some people should avoid it or take special precautions when using it such as women who are pregnant or planning to become pregnant.

Your healthcare provider will assess the potential risk of any adverse reaction between hyaluronic acid and any other medications you are taking. 

The Bottom Line

After reading this article, you should have a pretty good understanding as to why taking collagen with hyaluronic acid is an excellent option for looking and feeling your best! Together, collagen and hyaluronic acid are very effective!

For more great health tips and information, be sure to check out our Health and Nutrition BLOG. And do you want to make sure you are getting the best supplements for your health investment?

Head on over to our product page where you can be assured you’re getting the best quality supplements available on the market today. 

Organixx Clean Sourced Collagens blend contains five types of collagen from four sources. What’s more, it’s combined with targeted nutrients such as zinc, vitamin C, and vitamin B6 which specifically enhance the bioavailability and potency of collagen. Clean Sourced Collagens is formulated from the ground up to enhance and support your body’s natural ability to heal and rebuild itself from the INSIDE out.

Organixx Clean Sourced Collagens
Cassia Angustifolia: Better Than Hyaluronic Acid for Skin?

Nothing beats the substances and mechanisms that exist naturally in your own body for creating health and vitality. That being said, the next best thing is substances found in nature, such as phytonutrient-rich foods, herbs, and spices, that can support your body in similar ways. This is the case with Cassia angustifolia (aka senna) and skin health.

According to many experts, senna’s ability to mimic naturally occurring hyaluronic acid is safer and outperforms synthetically produced hyaluronic acid. That means it can be an amazing addition to your skincare routine, either solo or as a key ingredient in a quality skin-enhancing serum.

What Is Hyaluronic Acid?

Hyaluronic acid is a substance that the body produces which acts like a lubricant and a “moisture capturer.” It has a cushion-like effect between tissues and is found in the highest quantities in the joints and eyes. Research indicates that hyaluronic acid may play an important role in wound-healing as well [1].


Hyaluronic acid is also vital for the health of your skin since it is the molecular substance that helps skin retain moisture. High water content is what makes your skin resilient and pliable. Hyaluronic acid functions in the various layers of skin in different ways. It all adds up to one thing, however – giving your skin that plump glow of youth by helping it retain water [2].

Hyaluronic Acid Depletes As We Age

Just like collagen (another substance vital for skin health), hyaluronic acid gets depleted through external stressors such as:

It also responds to internal stressors such as:

The simple process of aging also has a detrimental effect on hyaluronic acid levels as time goes by.

The authors of a 2012 report for the journal Dermato Endocrinology describe how the process of on-going exposure to stressors as we age affect the skin’s important ability to retain water through hyaluronic acid [3]:

“Skin aging is a multifactorial process consisting of two distinct and independent mechanisms: intrinsic and extrinsic aging. Youthful skin retains its turgor, resilience and pliability, among others, due to its high content of water. Daily external injury, in addition to the normal process of aging, causes loss of moisture. The key molecule involved in skin moisture is hyaluronic acid (HA) that has unique capacity in retaining water.”


Externally Produced Hyaluronic Acid Sources: What You Need to Know

When our bodies lack hyaluronic acid or it is low, skin can become dry, dull-looking, saggy, and prone to skin infection and blemishes. It makes sense then that we would seek out external sources of hyaluronic acid directly, although this may not be optimal for everyone.

Most commercial moisturizers and other face lotions contain externally produced or harvested sources of hyaluronic acid, sometimes from questionable sources. For the most part, external hyaluronic acid is obtained in one of two ways:

  1. It can be extracted from animals – rooster comb or cows’ eyes, in particular.
  2. It can also be created artificially in the laboratory by harvesting it from Streptococcus bacteria typically grown on wheat grains [4].

Some people call externally obtained hyaluronic acid a “fountain of youth” since it is able to mimic internally produced hyaluronic acid enough to help the skin retain water.

Indeed, externally produced hyaluronic acid is used commonly in the conventional setting for joint and eye conditions. It is also used for skin conditions, such as for cases of severe, acute dermatitis [5] as well as in many skincare products aimed at combatting signs of aging.

Many people prefer not to use externally produced forms of hyaluronic acid for a variety of reasons. For example, vegans or people concerned about toxicity over the long term.

How the EWG Rates Hyaluronic Acid’s Safety

The much-respected consumer safety organization Environmental Working Group (EWG) gives hyaluronic acid an overall toxicity rating of “fair.” They cite data gaps in research as well as some studies that may indicate the potential for toxicity as the basis for their rating [6].

As with so many other substances that are put in commercial skincare products, very little research has been done on hyaluronic acid. Therefore, we can only speculate as to its safety overall. We can, however, use common sense.

GMO & Antibiotics Are a Concern


Commercial poultry operations and beef feedlots themselves are sadly some of the most toxic environments on the planet. The majority of commercial operations give the animals feed made from GMO-derived corn and soy [7]. In addition, the majority of antibiotics used in the United States – 80% according to recent reports – go to animals used in commercial meat production [8].

Externally derived hyaluronic acid may also contain a yet-unknown potential for toxicity. Think of it this way. Do you really want to put something on your face that was extracted from GMO-raised, heavily medicated animals or grown using one of the most insidiously pathogenic bacteria on earth?

By the way, Streptococci bacteria is responsible for many conditions including strep throat, scarlet fever, inflammation of the kidney, rheumatic fever, impetigo, and cellulitis [9-11].

A Plant-based Alternative to Hyaluronic Acid

Luckily, there is another way. If you’re someone who appreciates plant-based natural alternatives, then you should know about Cassia angustifolia, otherwise known as senna plant. In fact, using Cassia angustifolia seed polysaccharide may yield a better result for your skin health overall.

Cassia Angustifolia Seed Polysaccharide: Amazing Natural Substance for Skin!

Many individuals swear by facial beauty products that contain senna, or Cassia angustifolia – and for good reason.

Senna is originally from Africa and Arabia, although it is now grown all over the world. It has been used for thousands of years for its diuretic effects and especially as a curative for constipation. In modern times, it was discovered that it could also be used as a powerful beauty aid for the skin [12].

Senna’s molecular structure is very similar to hyaluronic acid. This means that it also has the ability to retain water. Senna seed polysaccharides, a natural ingredient in most quality, organic skincare products such as Organixx Skin Restore Vitamin C Serum, has two great effects:


Some experts claim that senna seed can hold up to 100 times its weight in water! A comprehensive 2006 evaluation of Cassia angustifolia seed published in the journal Pharmaceutical Biology confirmed the water-soluble nature of the polysaccharides in the seeds as well as its ability to retain water [13].

Senna is also a powerful antibacterial/antifungal that may be able to help with skin infections. A 2016 report published in the Journal of Pharmacognosy and Phytotherapy stated that Cassia Angustifolia extract “possesses remarkable antimicrobial activity and could act as an antifungal agent [14].”

How Cassia Angustifolia Seed Polysaccharides and Vitamin C Work Together

Cassia angustifolia seed polysaccharides draw moisture to the surface and keep it there for vibrant-looking skin. Vitamin C is the other side of this “dynamic duo.” The C is absolutely vital for the production of collagen in the dermis level.

Likewise, collagen is absolutely essential for skin cell renewal and repair. It is, in fact, what the skin is made up of in large part. It also plays a role in keeping skin soft, firm, and hydrated since it works together with hyaluronic acid to maintain a moist environment.

Skin hydration is important not just for beauty but for the integrity of the skin at a very basic level. Collagen requires a moist environment to stretch. When conditions are too dry, collagen strands will break and new tissue cannot form nor be repaired [15].

Organixx Skin Restore Vitamin C Serum with Cassia Angustifolia

Super-absorbable and high-antioxidant vitamin C is the key ingredient in Organixx Skin Restore Vitamin C Serum. Other 100% organic ingredients included in our unique formula are just as vital, however.

Besides Cassia angustifolia seed polysaccharides, other healing substances in Restore include natural aloe, vitamin E, kelp, Matrixyl® 3000 (a powerful peptide promoter), and MSM. Each ingredient lends its “unique talents” to the mix. Most importantly, they all contribute to a synergistic effect that can lead to beautiful, glowing, moisture-locked skin!

Discover Restore Vitamin C Serum… the most scientifically advanced topical vitamin C on earth, designed to keep your skin youthful, radiant, and healthy for the long term!

AnnieMak Restore Vitamin C Serum